Efficacy and safety of domestic semaglutide injection in patients with type 2 diabetes mellitus inadequately controlled with metformin
This multicenter, randomized, positive-controlled phase 3 equivalence clinical trial evaluated the efficacy and safety of domestic semaglutide injection in patients with type 2 diabetes mellitus inadequately controlled with metformin. Patients were randomized to an experimental group receiving domestic semaglutide injection and a control group receiving original semaglutide injection. The study compared the two treatments over 32 weeks.
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The trial demonstrated that domestic semaglutide injection has glucose-lowering efficacy equivalent to original semaglutide injection over 32 weeks, with similar safety profiles.
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