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Research

Mesenchymal stromal cell-based therapies for obesity-associated metabolic complications

This review summarizes current mechanistic insights, preclinical findings, and clinical data on MSC-based interventions for obesity-associated metabolic disorders. It notes that obesity impairs endogenous MSC function and that no randomized controlled trial has evaluated MSC therapy for obesity with weight loss as a primary endpoint.

What to check after reading

This is a review highlighting the challenge of impaired MSC function in obesity and the lack of obesity-specific randomized controlled trial evidence.

Source

PubMed ↗

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